Therapeutic implementation of human limb regeneration is a daring aim.Studying species that can regrow their lost appendages provides clues on how such a feat can be achieved in mammals.One of the unique features of regeneration-competent species lies in their ability to seal the amputation plane Unframed Baseball Photos with a scar-free wound epithelium.Subsequently, this wound epithelium advances and becomes a specialized wound epidermis (WE) which is hypothesized to be the essential component of regenerative success.Recently, the WE and specialized WE terminologies have been used interchangeably.
However, these tissues were historically separated, and contemporary limb regeneration studies have provided critical new information which allows us to distinguish them.Here, I will summarize tissue-level observations and recently identified cell types of WE and their specialized forms Feeder Drive Rollers in different regeneration models.